Inflammatory Skin Disease

Inflammatory Dermatoses

Evidence Level C Emerging Evidence

Case-level and small-cohort evidence supports HBOT as an adjunct in selected inflammatory skin conditions, primarily atopic dermatitis and psoriasis. A 2025 review and a 2021 paediatric study describe reductions in pruritus, lesion severity, and Staphylococcus aureus colonisation in severe atopic dermatitis after HBOT cycles. Two 2009 case reports document remission of psoriasis vulgaris with HBOT (one pustular/arthropathic case after 6 sessions at 2.8 ATA × 60 min; one plaque case improving after 15 sessions at 2.0 ATA × 90 min). Other inflammatory dermatoses — hidradenitis suppurativa, livedoid vasculopathy, pyoderma gangrenosum — have been described in early-stage clinical reports but lack robust supporting trials. Protocols vary widely and are not standardised; HBOT is positioned as adjunctive, not first-line.

Treatment protocol

Protocol

Pressure

2.0 – 2.8 ATA

Duration

60 – 90 min

Sessions

6 – 30 (highly variable)

Frequency

Daily, protocol-dependent

Evidence basis: Case Reports & Small Studies (not standardised)

References:

See full citations on the references page.