Reference

Protocol Comparison

Side-by-side comparison of HBOT protocols across FDA-approved indications and longevity applications. Cmd-P / Ctrl-P prints cleanly to PDF.

FDA-approved indications (19)

Indication Pressure Duration Sessions Frequency Level Basis
Air or Gas Embolism

Acute Ischemias

2.8 – 3.0 ATA 90 min [object Object] [object Object] A UHMS / Emergency Standard
Carbon Monoxide Poisoning

Toxicities

2.4 – 2.8 ATA 90 min [object Object] [object Object] A UHMS / Emergency Standard
Clostridial Myositis & Myonecrosis (Gas Gangrene)

Infectious Diseases

2.0 – 2.5 ATA 90 min [object Object] [object Object] A UHMS / Standard of Care
Crush Injury & Compartment Syndrome

Acute Ischemias

2.0 – 2.4 ATA 90 min [object Object] [object Object] A UHMS / FDA-Approved
Decompression Sickness

Gas/Bubble Disorders

2.0 – 2.5 ATA 90 min [object Object] [object Object] A UHMS / Standard of Care
Enhancement of Healing in Selected Problem Wounds

Wound Healing

2.0 – 2.4 ATA 90 min [object Object] [object Object] A UHMS / Standard of Care
Exceptional Blood Loss Anemia

Infectious Diseases

2.0 – 2.5 ATA 90 min [object Object] [object Object] B UHMS / Standard of Care
Intracranial Abscess

Infectious Diseases

2.0 – 2.5 ATA 90 min [object Object] [object Object] B UHMS / Standard of Care
Necrotizing Soft Tissue Infections

Infectious Diseases

2.0 – 2.5 ATA 90 min [object Object] [object Object] A UHMS / Standard of Care
Refractory Osteomyelitis

Infectious Diseases

2.0 – 2.4 ATA 90 min [object Object] [object Object] A UHMS / Standard of Care
Delayed Radiation Injury (Soft Tissue & Bony Necrosis)

Wound Healing

2.0 – 2.4 ATA 90 min [object Object] [object Object] A UHMS / Standard of Care
Compromised Skin Grafts & Flaps

Acute Ischemias

2.0 – 2.4 ATA 90 min [object Object] [object Object] B UHMS / Standard of Care
Idiopathic Sudden Sensorineural Hearing Loss

Sensory Disorders

2.0 – 2.5 ATA 90 min [object Object] [object Object] B UHMS / Standard of Care
Central Retinal Artery Occlusion

Sensory Disorders

2.0 – 2.8 ATA 90 min [object Object] [object Object] B UHMS / Emergency Standard
Long COVID

Post-Viral Syndromes

2.0 ATA 90 min [object Object] [object Object] B Zilberman-Itskovich et al., 2022 (RCT)
Fibromyalgia

Chronic Pain Syndromes

2.0 ATA 90 min [object Object] [object Object] B Efrati et al., 2015 (prospective controlled trial)
Inflammatory Dermatoses

Inflammatory Skin Disease

2.0 – 2.8 ATA 60 – 90 min [object Object] [object Object] C Case Reports & Small Studies (not standardised)
Aesthetic & Reconstructive Recovery

Aesthetic & Reconstructive Surgery

2.0 – 2.5 ATA 60 – 90 min [object Object] [object Object] B Case–Control Study (Neel et al., 2023) + Reviews
Endometriosis

Reproductive Health

Not standardised Not standardised [object Object] [object Object] C Translational (animal models) + Registered Trial Awaiting Results

Longevity applications (6)

Application Pressure Duration Sessions Frequency Basis
Telomere Lengthening 2.0 ATA 90 min [object Object] [object Object] Hadanny et al., 2020 (RCT)
Senescent Cell Clearance 2.0 ATA 90 min [object Object] [object Object] Hadanny et al., 2020 (RCT)
Cognitive Enhancement 2.0 ATA 90 min [object Object] [object Object] Hadanny et al., 2020 (RCT)
Stem Cell Mobilization 2.0 – 2.4 ATA 90 min [object Object] [object Object] Thom et al., 2006 / Clinical Research
Athletic Performance & Recovery 1.5 – 2.4 ATA 60 – 90 min [object Object] [object Object] Systematic Review & Meta-Analysis
Collagen Production & Skin Health 2.0 – 2.4 ATA 90 min [object Object] [object Object] Clinical Research

All protocols are sourced from peer-reviewed publications cited on each indication's detail page. Evidence levels follow UHMS grading criteria. To export this matrix as PDF, use your browser's print function (Cmd-P / Ctrl-P).